Editorial:

S. Ewig and T. Welte

Evaluation of guidelines for community-acquired pneumonia: a story of confounders, surprises and challenges
Eur Respir J 2008 32: 823-825. [Full Text] [PDF]  

X. Trepat and R. Farré

Alveolar permeability and stretch: too far, too fast
Eur Respir J 2008 32: 826-828. [Full Text] [PDF]  

S. Suissa

Lung function decline in COPD trials: bias from regression to the mean
Eur Respir J 2008 32: 829-831. [Full Text] [PDF]  

Perspective:

B. M. Vanaudenaerde, I. Meyts, R. Vos, N. Geudens, W. De Wever, E. K. Verbeken, D. E. Van Raemdonck, L. J. Dupont, and G. M. Verleden

A dichotomy in bronchiolitis obliterans syndrome after lung transplantation revealed by azithromycin therapy
Eur Respir J 2008 32: 832-842. [Abstract] [Full Text] [PDF]  

N. S. Godtfredsen, T. H. Lam, T. T. Hansel, M. E. Leon, N. Gray, C. Dresler, D. M. Burns, E. Prescott, and J. Vestbo

COPD-related morbidity and mortality after smoking cessation: status of the evidence
Eur Respir J 2008 32: 844-853. [Abstract] [Full Text] [PDF]  

Original Articles: Cell biology of lung injury:

T. S. Cohen, K. J. Cavanaugh, and S. S. Margulies

Frequency and peak stretch magnitude affect alveolar epithelial permeability
Eur Respir J 2008 32: 854-861. [Abstract] [Full Text] [PDF]  

N. Geudens, M. Van de Wouwer, B. M. Vanaudenaerde, R. Vos, C. Van De Wauwer, G. M. Verleden, E. Verbeken, T. Lerut, D. E. M. Van Raemdonck, and E. M. Conway

The lectin-like domain of thrombomodulin protects against ischaemia–reperfusion lung injury
Eur Respir J 2008 32: 862-870. [Abstract] [Full Text] [PDF]  

Original Articles: Cell biology of pulmonary hypertension:

J. Sevilla-Pérez, M. Königshoff, G. Kwapiszewska, O. V. Amarie, W. Seeger, N. Weissmann, R. T. Schermuly, R. E. Morty, and O. Eickelberg

Shroom expression is attenuated in pulmonary arterial hypertension
Eur Respir J 2008 32: 871-880. [Abstract] [Full Text] [PDF]  

R. T. Schermuly, J-P. Stasch, S. S. Pullamsetti, R. Middendorff, D. Müller, K-D. Schlüter, A. Dingendorf, S. Hackemack, E. Kolosionek, C. Kaulen, R. Dumitrascu, N. Weissmann, J. Mittendorf, W. Klepetko, W. Seeger, H. A. Ghofrani, and F. Grimminger

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
Eur Respir J 2008 32: 881-891. [Abstract] [Full Text] [PDF] [Supplementary materials, methods and figures]  

Original Articles: Community-acquired pneumonia:

P. G. Dambrava, A. Torres, X. Vallès, J. Mensa, M. A. Marcos, G. Peñarroja, M. Camps, R. Estruch, M. Sánchez, R. Menéndez, and M. S. Niederman

Adherence to guidelines’ empirical antibiotic recommendations and community-acquired pneumonia outcome
Eur Respir J 2008 32: 892-901. [Abstract] [Full Text] [PDF]  

F. Blasi, I. Iori, A. Bulfoni, S. Corrao, S. Costantino, and D. Legnani

Can CAP guideline adherence improve patient outcome in internal medicine departments?
Eur Respir J 2008 32: 902-910. [Abstract] [Full Text] [PDF] [Supplementary tables]  

Original Articles: Lung cancer:

M-Y. Li, J. Yip, M. K. Y. Hsin, T. S. K. Mok, Y. Wu, M. J. Underwood, and G. G. Chen

Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis
Eur Respir J 2008 32: 911-923. [Abstract] [Full Text] [PDF]  

S-G. Wu, C-H. Gow, C-J. Yu, Y-L. Chang, C-H. Yang, Y-C. Hsu, J-Y. Shih, Y-C. Lee, and P-C. Yang

Frequent epidermal growth factor receptor gene mutations in malignant pleural effusion of lung adenocarcinoma
Eur Respir J 2008 32: 924-930. [Abstract] [Full Text] [PDF]  

Original Articles: Genetics in COPD:

S. Chappell, L. Daly, K. Morgan, T. Guetta-Baranes, J. Roca, R. Rabinovich, J. Lotya, A. B. Millar, S. C. Donnelly, V. Keatings, W. MacNee, J. Stolk, P. S. Hiemstra, M. Miniati, S. Monti, C. M. O’Connor, and N. Kalsheker

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD
Eur Respir J 2008 32: 931-937. [Abstract] [Full Text] [PDF] [Supplementary tables]  

M. G. Foreman, D. L. DeMeo, C. P. Hersh, V. J. Carey, V. S. Fan, J. J. Reilly, S. D. Shapiro, and E. K. Silverman

Polymorphic variation in surfactant protein B is associated with COPD exacerbations
Eur Respir J 2008 32: 938-944. [Abstract] [Full Text] [PDF] [Supplementary table]  

Original Articles: Clinical COPD:

T. R. J. Schermer, I. J. M. Smeele, B. P. A. Thoonen, A. E. M. Lucas, J. G. Grootens, T. J. van Boxem, Y. F. Heijdra, and C. van Weel

Current clinical guideline definitions of airflow obstruction and COPD overdiagnosis in primary care
Eur Respir J 2008 32: 945-952. [Abstract] [Full Text] [PDF]  

N. Roche, M. Zureik, D. Soussan, F. Neukirch, D. Perrotin, and the Urgence BPCO (COPD Emergency) Scientific Committee and investigators

Predictors of outcomes in COPD exacerbation cases presenting to the emergency department
Eur Respir J 2008 32: 953-961. [Abstract] [Full Text] [PDF]  

D. M. Mannino, D. Thorn, A. Swensen, and F. Holguin

Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
Eur Respir J 2008 32: 962-969. [Abstract] [Full Text] [PDF]  

Original Articles: Asthma:

D. S. Southam, R. Ellis, J. Wattie, S. Young, and M. D. Inman

Budesonide prevents but does not reverse sustained airway hyperresponsiveness in mice
Eur Respir J 2008 32: 970-978. [Abstract] [Full Text] [PDF] [Supplementary methods, results, discussion and figures]  

A. Bernard, M. Nickmilder, and C. Voisin

Outdoor swimming pools and the risks of asthma and allergies during adolescence
Eur Respir J 2008 32: 979-988. [Abstract] [Full Text] [PDF]  

P. Rytilä, L. Ghaly, S. Varghese, W. Chung, O. Selroos, T. Haahtela on behalf of the Airway Inflammation Study group

Treatment with inhaled steroids in patients with symptoms suggestive of asthma but with normal lung function
Eur Respir J 2008 32: 989-996. [Abstract] [Full Text] [PDF]  

Original Articles: Occupational exposures:

J-P. Rioux, J-L. Malo, J. L’Archevêque, K. Rabhi, and M. Labrecque

Workplace-specific challenges as a contribution to the diagnosis of occupational asthma
Eur Respir J 2008 32: 997-1003. [Abstract] [Full Text] [PDF]  

Original Articles: Pulmonary fibrosis:

M. Molina-Molina, A. Xaubet, X. Li, A. Abdul-Hafez, K. Friderici, K. Jernigan, W. Fu, Q. Ding, J. Pereda, A. Serrano-Mollar, A. Casanova, E. Rodríguez-Becerra, F. Morell, J. Ancochea, C. Picado, and B. D. Uhal

Angiotensinogen gene G-6A polymorphism influences idiopathic pulmonary fibrosis disease progression
Eur Respir J 2008 32: 1004-1008. [Abstract] [Full Text] [PDF]  

Original Articles: Sleep-disordered breathing:

M. A. Arias, F. García-Río, A. Alonso-Fernández, Á. Hernanz, R. Hidalgo, V. Martínez-Mateo, S. Bartolomé, and L. Rodríguez-Padial

CPAP decreases plasma levels of soluble tumour necrosis factor- receptor 1 in obstructive sleep apnoea
Eur Respir J 2008 32: 1009-1015. [Abstract] [Full Text] [PDF]  

A. Sánchez-Armengol, A. Ruiz-García, C. Carmona-Bernal, G. Botebol-Benhamou, E. García-Díaz, J. Polo-Padillo, J. L. López-Campos, and F. Capote

Clinical and polygraphic evolution of sleep-related breathing disorders in adolescents
Eur Respir J 2008 32: 1016-1022. [Abstract] [Full Text] [PDF]  

Original Articles: Tuberculosis:

G. H. Bothamley, L. Ditiu, G. B. Migliori, C. Lange, and TBNET contributors

Active case finding of tuberculosis in Europe: a Tuberculosis Network European Trials Group (TBNET) survey
Eur Respir J 2008 32: 1023-1030. [Abstract] [Full Text] [PDF] [Supplementary information][CME form]  

D. K. Kim, H. J. Kim, S-Y. Kwon, H-I. Yoon, C-T. Lee, Y. W. Kim, H. S. Chung, S. K. Han, Y-S. Shim, and J-H. Lee

Nutritional deficit as a negative prognostic factor in patients with miliary tuberculosis
Eur Respir J 2008 32: 1031-1036. [Abstract] [Full Text] [PDF]  

Original Articles: Steroids and pneumonia:

O. Sibila, C. M. Luna, C. Agustí, S. Baquero, S. Gando, J. R. Patrón, J. G. Morato, R. Absi, N. Bassi, and A. Torres

Effects of glucocorticoids in ventilated piglets with severe pneumonia
Eur Respir J 2008 32: 1037-1046. [Abstract] [Full Text] [PDF]  

Original Articles: Steroids and bronchiectasis:

J. Holme, J. W. Tomlinson, R. A. Stockley, P. M. Stewart, N. Barlow, and A. L. Sullivan

Adrenal suppression in bronchiectasis and the impact of inhaled corticosteroids
Eur Respir J 2008 32: 1047-1052. [Abstract] [Full Text] [PDF]  

Original Articles: Technological developments:

X. Muñoz, F. Torres, G. Sampol, J. Rios, S. Martí, and E. Escrich

Accuracy and reliability of pulse oximetry at different arterial carbon dioxide pressure levels
Eur Respir J 2008 32: 1053-1059. [Abstract] [Full Text] [PDF]  

H. Nakano, T. Tanigawa, Y. Ohnishi, H. Uemori, K. Senzaki, T. Furukawa, and S. Nishima

Validation of a single-channel airflow monitor for screening of sleep-disordered breathing
Eur Respir J 2008 32: 1060-1067. [Abstract] [Full Text] [PDF]  

Review:

P-R. Burgel and J. A. Nadel

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases
Eur Respir J 2008 32: 1068-1081. [Abstract] [Full Text] [PDF]  

Series:

P. Lévy, J-L. Pépin, C. Arnaud, R. Tamisier, J-C. Borel, M. Dematteis, D. Godin-Ribuot, and C. Ribuot

Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives
Eur Respir J 2008 32: 1082-1095. [Abstract] [Full Text] [PDF]  

ERS Task Force:

P. L. P. Brand, E. Baraldi, H. Bisgaard, A. L. Boner, J. A. Castro-Rodriguez, A. Custovic, J. de Blic, J. C. de Jongste, E. Eber, M. L. Everard, U. Frey, M. Gappa, L. Garcia-Marcos, J. Grigg, W. Lenney, P. Le Souëf, S. McKenzie, P. J. F. M. Merkus, F. Midulla, J. Y. Paton, G. Piacentini, P. Pohunek, G. A. Rossi, P. Seddon, M. Silverman, P. D. Sly, S. Stick, A. Valiulis, W. M. C. van Aalderen, J. H. Wildhaber, G. Wennergren, N. Wilson, Z. Zivkovic, and A. Bush

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach
Eur Respir J 2008 32: 1096-1110. [Abstract] [Full Text] [PDF]  

Case Study:

B. Yates, A. De Soyza, R. Harkawat, and C. Stenton

Occupational asthma caused by Arabidopsis thaliana: a case of laboratory plant allergy
Eur Respir J 2008 32: 1111-1112. [Abstract] [Full Text] [PDF]  

M. Eichinger, S. Walterspacher, T. Scholz, K. Tetzlaff, K. Röcker, C-M. Muth, M. Puderbach, H-U. Kauczor, S. Sorichter for the breath-hold diving study group of Baden-Württemberg

Lung hyperinflation: foe or friend?
Eur Respir J 2008 32: 1113-1116. [Abstract] [Full Text] [PDF] [Supplementary video]  

Correspondence:

G. Invernizzi, R. Boffi, A. Ruprecht, A. Lazzaro, and L. M. Fabbri

Passive smoking and asthma death
Eur Respir J 2008 32: 1117. [Full Text] [PDF]  

S. Suissa

Exacerbations and intent-to-treat analyses in randomised trials
Eur Respir J 2008 32: 1117-1118. [Full Text] [PDF]  

L-P. Boulet

Asymptomatic airway hyperresponsiveness: what does it mean?
Eur Respir J 2008 32: 1118-1119. [Full Text] [PDF]  

M. Duong, A. M. Wilson, L. Jayaram, M. Dolovich, and F. Hargreave

The effect of inhaled lidocaine–hydrofluoroalkane 134a in prednisone-dependent eosinophilic bronchitis
Eur Respir J 2008 32: 1119-1122. [Full Text] [PDF]  

J. Barben and J. Schmid

Dental units as infection sources of Pseudomonas aeruginosa
Eur Respir J 2008 32: 1122-1123. [Full Text] [PDF]  

M. P. Wise, D. W. Williams, M. A. Lewis, J. G. Thomas, and P. J. Frost

Impact of poor dental health on pneumonia
Eur Respir J 2008 32: 1123-1124. [Full Text] [PDF]  

S. Chow, D. H. Yates, and P. S. Thomas

Reproducibility of exhaled breath condensate markers
Eur Respir J 2008 32: 1124-1126. [Full Text] [PDF]  

A. Paradiso, S. Tommasi, R. Pinto, G. E. Carpagnano, and M. P. Foschino-Barbaro

Exhaled breath condensate is not suitable to detect EGFR somatic mutations
Eur Respir J 2008 32: 1126-1127. [Full Text] [PDF]  

C. Iwuji, A. Rosich-Medina, N. Swaminathan, D. Baguley, C. Kirwin, K. Austin, and R. J. Kurukulaaratchy

The potential for patient-led COPD admission avoidance schemes
Eur Respir J 2008 32: 1128-1129. [Full Text] [PDF]  

C. Laurin, K. L. Lavoie, and S. L. Bacon

Relationship between depression and exacerbations in COPD: a response
Eur Respir J 2008 32: 1129-1130. [Full Text] [PDF]  

L. Mascitelli, F. Pezzetta, and M. R. Goldstein

Inhibition of the renin–angiotensin system in severe COPD
Eur Respir J 2008 32: 1130. [Full Text] [PDF]  

P. M. A. Calverley and P. Albert

From the authors
Eur Respir J 2008 32: 1131. [Full Text] [PDF]  

W. H. Ibrahim

Massive haemoptysis: the definition should be revised
Eur Respir J 2008 32: 1131-1132. [Full Text] [PDF]  

G. G. Riario Sforza and C. Incorvaia

Mortality predictive capacity of the 6-min walk distance
Eur Respir J 2008 32: 1132. [Full Text] [PDF]  

C. G. Cote

From the authors
Eur Respir J 2008 32: 1132-1133. [Full Text] [PDF]  

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