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Eur Respir J 1996; 9: 1092-1093
Copyright © ERS Journals Ltd 1996

Case Studies

Continuous positive airway pressure is effective in treating upper airway oedema

F Barbe, S Pons, B Togores, J Sauleda, R Soler, and AG Agusti

The case of a patient with diffuse idiopathic skeletal hyperostosis (DISH) and upper airway oedema, is described. The patient presented with alveolar hypoventilation and obstructive apnoeas during sleep. Intravenous steroids (methylprednisolone, 160 mg.day-1) for 5 days did not reduce the oedema. However, it was rapidly reversed by the use of nasal continuous positive airway pressure (nCPAP). In addition, daytime pulmonary gas exchange was improved and sleep apnoea abolished. This beneficial effect made tracheostomy unnecessary. This case report suggests that CPAP can be a potentially useful therapeutic alternative to tracheostomy in the clinical management of upper airway oedema.


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S. Willing, M. S. Pedro, H. S. Driver, P. Munt, and M. F. Fitzpatrick
The acute impact of continuous positive airway pressure on nasal resistance: a randomized controlled comparison
J Appl Physiol, March 1, 2007; 102(3): 1214 - 1219.
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Copyright © 1996 by the European Respiratory Society.