ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Permissions
Right arrowRequest Permissions
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Okubadejo, A.
Right arrow Articles by Wedzicha, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Okubadejo, A.
Right arrow Articles by Wedzicha, J.
Eur Respir J 1996; 9: 2335-2339
Copyright © ERS Journals Ltd 1996

Original Articles

Does long-term oxygen therapy affect quality of life in patients with chronic obstructive pulmonary disease and severe hypoxaemia?

AA Okubadejo, EA Paul, PW Jones, and JA Wedzicha

Long-term oxygen therapy (LTOT) improves survival in patients with hypoxaemic chronic obstructive pulmonary disease (COPD), but previous studies using general health measures have shown no effect on quality of life (QoL). In this study, the effect of LTOT on QoL was assessed using a disease-specific health measure, the St George's Respiratory Questionnaire (SGRQ). Twenty three hypoxaemic COPD patients (15 females and 8 males) were studied before and after starting LTOT: median age 71 (range 47-82) yrs, mean (SD) forced expiratory volume in one second (FEV1) 0.75 (0.22) L, arterial oxygen tension (Pa,O2) 6.95 (0.75) kPa, arterial carbon dioxide tension (Pa,CO2) 6.52 (1.21) kPa. A control group comprised 18 COPD patients (6 females and 12 males) with less severe hypoxaemia: median age 72 (range 58-85) yrs, FEV1 0.94 (0.33) L, Pa,O2 8.17 (0.94) kPa, Pa,CO2 6.02 (0.75) kPa. QoL was measured at baseline, 2 weeks, 3 and 6 months. The LTOT group had higher SGRQ total scores than controls (p<0.05) at all visits, implying lower QoL. Repeated measures analysis of variance showed no effect of LTOT on QoL over 6 months (F=0.43, p=0.79). In this study we detected no change in quality of life using a disease-specific health measure in patients with severe chronic obstructive pulmonary disease using an oxygen concentrator to provide long-term oxygen therapy.


This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
T. L. Croxton, W. C. Bailey, and for the NHLBI Working Group on Long-term Oxygen Tr
Long-term Oxygen Treatment in Chronic Obstructive Pulmonary Disease: Recommendations for Future Research: An NHLBI Workshop Report
Am. J. Respir. Crit. Care Med., August 15, 2006; 174(4): 373 - 378.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
C. A. Sant'Anna, R. Stelmach, M. I. Zanetti Feltrin, W. J. Filho, T. Chiba, and A. Cukier
Evaluation of Health-Related Quality of Life in Low-Income Patients With COPD Receiving Long-term Oxygen Therapy
Chest, January 1, 2003; 123(1): 136 - 141.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
J.A. Wedzicha and J-F. Muir
Noninvasive ventilation in chronic obstructive pulmonary disease, bronchiectasis and cystic fibrosis
Eur. Respir. J., September 1, 2002; 20(3): 777 - 784.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Ferrer, C. Villasante, J. Alonso, V. Sobradillo, R. Gabriel, G. Vilagut, J.F. Masa, J.L. Viejo, C.A. Jimenez-Ruiz, and M. Miravitlles
Interpretation of quality of life scores from the St George's Respiratory Questionnaire
Eur. Respir. J., March 1, 2002; 19(3): 405 - 413.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
S E Jones, S Packham, M Hebden, and A P Smith
Domiciliary nocturnal intermittent positive pressure ventilation in patients with respiratory failure due to severe COPD: long term follow up and effect on survival
Thorax, June 1, 1998; 53(6): 495 - 498.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1996 by the European Respiratory Society.