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Eur Respir J 1994; 7: 1192-1193
Copyright © ERS Journals Ltd 1994

Case Studies

Small cell lung cancer with paraneoplastic nephrotic syndrome

ES Boon, AA Vrij, C Nieuwhof, JA van Noord, and E Zeppenfeldt

We present a case of nephrotic syndrome, associated with small cell lung carcinoma. Renal biopsy revealed membranous glomerulonephritis, probably due to immune complex deposition with tumour antigen. Complete remission of the small cell lung carcinoma after chemotherapy was followed by regression of the nephrotic syndrome. This regression persisted even when brain metastases developed, without simultaneous relapse of tumour outside the central nervous system.


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B. Ebert, K. Shaffer, and H. Rennke
Some Unusual Paraneoplastic Syndromes: CASE 4. PARANEOPLASTIC NEPHROTIC SYNDROME IN A PATIENT WITH LUNG CANCER
J. Clin. Oncol., July 1, 2003; 21(13): 2624 - 2625.
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