ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Order Full text via Infotrieve
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lamblin, G
Right arrow Articles by Roussel, P
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lamblin, G
Right arrow Articles by Roussel, P
Eur Respir J 1992; 5: 247-256
Copyright © ERS Journals Ltd 1992

Original Articles

Human respiratory mucins

G Lamblin, JP Aubert, JM Perini, A Klein, N Porchet, P Degand, and P Roussel

Human respiratory mucins are secreted by goblet cells and mucous glands of the respiratory mucosa. They consist of a broad family of complex glycoproteins with different peptides, or apomucins, corresponding to several genes located on at least three different chromosomes. Glycosylation, the major posttranslational phenomenon, is responsible for about 70-80% of the weight of mucins: it produces an extraordinary diversity of O-glycosidically linked carbohydrate chains which are expressed as several hundreds of different chains in the mucins of a single individual. The variety of mucin peptides and the diversity of carbohydrate chains probably allows many interactions, especially with microorganisms: this may be an essential factor in the defence of the underlying respiratory mucosa.


This article has been cited by other articles:


Home page
 GlycobiologyHome page
B. Xia, J. A. Royall, G. Damera, G. P. Sachdev, and R. D. Cummings
Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis
Glycobiology, August 1, 2005; 15(8): 747 - 775.
[Abstract] [Full Text] [PDF]

Home page
 J. Dent. Res.Home page
J. Li, E.J. Helmerhorst, R.F. Troxler, and F.G. Oppenheim
Identification of in vivo Pellicle Constituents by Analysis of Serum Immune Responses
J. Dent. Res., January 1, 2004; 83(1): 60 - 64.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. D. Leikauf, M. T. Borchers, D. R. Prows, and L. G. Simpson
Mucin Apoprotein Expression in COPD*
Chest, May 1, 2002; 121(5_suppl): 166S - 182S.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
M.-P. Buisine, L. Devisme, M.-C. Copin, M. Durand-Réville, B. Gosselin, J.-P. Aubert, and N. Porchet
Developmental Mucin Gene Expression in the Human Respiratory Tract
Am. J. Respir. Cell Mol. Biol., February 1, 1999; 20(2): 209 - 218.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
C. HERMANS and A. BERNARD
Lung Epithelium-specific Proteins . Characteristics and Potential Applications as Markers
Am. J. Respir. Crit. Care Med., February 1, 1999; 159(2): 646 - 678.
[Full Text]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
M. Ulrich, S. Herbert, J. Berger, G. Bellon, D. Louis, G. Münker, and G. Döring
Localization of Staphylococcus aureus in Infected Airways of Patients with Cystic Fibrosis and in a Cell Culture Model of S. aureus Adherence
Am. J. Respir. Cell Mol. Biol., July 1, 1998; 19(1): 83 - 91.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by the European Respiratory Society.