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Copyright ©ERS Journals Ltd 2007
Evidence on measures for the prevention of ventilator-associated pneumonia
1 Intensive Care Unit, Hospital Universitario de Canarias, La Laguna, Tenerife, 3 Intensive Care Dept, Joan XXIII University Hospital, and 4 University Rovira i Virgili Medical School, Pere Virgili Health Institut, Tarragona, Spain, 2 Critical Care Dept, Ghent University Hospital, Ghent, Belgium.
CORRESPONDENCE: L. Lorente, Intensive Care Unit, Hospital Universitario de Canarias, C/ Ofra s/n, La Laguna, Tenerife, 38320, Spain. Fax: 34 22662245. E-mail: lorentemartin{at}msn.com
Keywords: Ventilator-associated pneumonia
Received: April 20, 2007
Accepted July 3, 2007
Ventilator-associated pneumonia (VAP) continues to be an important cause of morbidity and mortality in ventilated patients.
Evidence-based guidelines have been issued since 2001 by the European Task Force on ventilator-associated pneumonia, the Centers for Disease Control and Prevention, the Canadian Critical Care Society, and also by the American Thoracic Society and Infectious Diseases Society of America, which have produced a joint set of recommendations.
The present review article is based on a comparison of these guidelines, together with an update of further publications in the literature. The 100,000 Lives campaign, endorsed by leading US agencies and societies, states that all ventilated patients should receive a ventilator bundle to reduce the incidence of VAP.
The present review article is useful for identifying evidence-based processes that can be modified to improve patients' safety.
This article has been cited by other articles:
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  C. Lizy, N. Brusselaers, S. Labeau, D. Vandijck, D. De Wandel, D. Vogelaers, and S. Blot Oral Care, Ventilator-Associated Pneumonia, and Counting Cultures Am. J. Crit. Care., November 1, 2009; 18(6): 507 - 509. [Full Text] [PDF]
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 A. Pobo, T. Lisboa, A. Rodriguez, R. Sole, M. Magret, S. Trefler, F. Gomez, J. Rello, and for the RASPALL Study Investigators A Randomized Trial of Dental Brushing for Preventing Ventilator-Associated Pneumonia Chest, August 1, 2009; 136(2): 433 - 439. [Abstract] [Full Text] [PDF]
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 V. Zaydfudim, L. A. Dossett, J. M. Starmer, P. G. Arbogast, I. D. Feurer, W. A. Ray, A. K. May, and C. W. Pinson Implementation of a Real-time Compliance Dashboard to Help Reduce SICU Ventilator-Associated Pneumonia With the Ventilator Bundle Arch Surg, July 1, 2009; 144(7): 656 - 662. [Abstract] [Full Text] [PDF]
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 K. Reppe, T. Tschernig, A. Luhrmann, V. van Laak, K. Grote, M. V. Zemlin, B. Gutbier, H. C. Muller, M. Kursar, H. Schutte, et al. Immunostimulation with Macrophage-Activating Lipopeptide-2 Increased Survival in Murine Pneumonia Am. J. Respir. Cell Mol. Biol., April 1, 2009; 40(4): 474 - 481. [Abstract] [Full Text] [PDF]
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D. E. Craven and K. Hjalmarson Prophylaxis of Ventilator-Associated Pneumonia: Changing Culture and Strategies to Trump Disease Chest, November 1, 2008; 134(5): 898 - 900. [Full Text] [PDF]
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 L. Silvestri, H. K. F. van Saene, M. A. de la Cal, R. E. Sarginson, and C. Thomann Prevention of ventilator-associated pneumonia by selective decontamination of the digestive tract Eur. Respir. J., July 1, 2008; 32(1): 241 - 243. [Full Text] [PDF]
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M. E. Falagas and I. I. Siempos Prevention of ventilator-associated pneumonia: possible role of antimicrobials administered via the respiratory tract Eur. Respir. J., May 1, 2008; 31(5): 1138 - 1139. [Full Text] [PDF]
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