ERJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Eur Respir J 2005; 26:453-457
Copyright ©ERS Journals Ltd 2005
doi: 10.1183/09031936.05.00015205

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Permissions
Right arrowRequest Permissions
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (5)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Struben, V. M. D.
Right arrow Articles by de Jongste, J. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Struben, V. M. D.
Right arrow Articles by de Jongste, J. C.

Nasal NO: normal values in children age 6 through to 17 years

V. M. D. Struben1, M. H. Wieringa1, C. J. Mantingh1, C. Bommeljé1, M. Don2, L. Feenstra1 and J. C. de Jongste3

1 Dept of Otolaryngology, and 3 Dept of Paediatric Respiratory Medicine, Erasmus MC, Rotterdam, The Netherlands. 2 Dept of Paediatrics, School of Medicine DPMSC, University of Udine, Italy.

CORRESPONDENCE: J. C. de Jongste, Erasmus medical centre/Sophia Children's Hospital, Dept Paediatric Respiratory Medicine, Dr. Molewaterplein 60, 3015 GD Rotterdam, The Netherlands. Fax: 31 104636811. E-mail: j.c.dejongste@erasmusmc.nl

Keywords: Children, nasal nitric oxide, normal values

Received: February 10, 2005
Accepted May 4, 2005

The present study is an assessment of normal values of nasal nitric oxide (nNO) in healthy children.

Healthy children aged between 6–17 yrs were recruited from three schools in Rotterdam (The Netherlands). Breath was held for 10 s, while air was extracted from one nostril at 700 mL·min–1. The mean nNO value at the response plateau after 7–10 s was recorded and the average of three measurements was used.

In total, 340 children participated; the male:female ratio was 156:184. Three reliable measurements were available in 85% of the children. The nNO concentrations were distributed normally (mean 449 ppb, SD 115). They were not associated with sex, passive smoking or body mass index. In children aged <12 yrs nNO correlated positively with age, history of adenoidectomy and ambient NO. In children aged ≥12 yrs ambient NO was the only significant modifier. Prediction rules for nNO values in children were formulated.

In conclusion, the current study presents normal values for nasal nitric oxide in children, which can be used to assess the value of nasal nitric oxide in respiratory illnesses.




This article has been cited by other articles:


Home page
 Arch. Dis. Child.Home page
A Bodini, S Rugolotto, U Pradal, G Zanotto, and D Peroni
Nasal nitric oxide for early diagnosis of familial primary ciliary dyskinesia
Arch. Dis. Child., May 1, 2008; 93(5): 452 - 453.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the European Respiratory Society.