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Eur Respir J 1997; 10: 2898-2901
Copyright © ERS Journals Ltd 1997

Case Studies

Pleural effusion during bromocriptine exposure in two patients with pre-existing asbestos pleural plaques: a relationship?

C Knoop, M Mairesse, C Lenclud, PA Gevenois, and P De Vuyst

Two patients with pleural plaques developed pleural effusion and subsequent diffuse pleural fibrosis 50 and 39 yrs after their first exposure to asbestos. The diagnosis of benign asbestos pleural effusion was suggested, but the work-up finally suggested bromocriptine-induced pleural disease in both patients. These two cases illustrate that drug-induced pleural effusion is an important differential diagnosis of benign asbestos pleural effusion. It is, moreover, possible that pre-existing asbestos pleural lesions, or even asbestos exposure, increases the risk of developing bromocriptine-induced pleural disease.


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S. Y. Morelock and S. A. Sahn
Drugs and the Pleura
Chest, July 1, 1999; 116(1): 212 - 221.
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